João B Pesquero Selected Research

Kininogens (Kininogen)

1/2019	Kinin-B2 Receptor Activity in Skeletal Muscle Regeneration and Myoblast Differentiation.
5/2012	Intracellular proteolysis of kininogen by malaria parasites promotes release of active kinins.
9/2009	Kinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis.
11/2006	Cooperative activation of TLR2 and bradykinin B2 receptor is required for induction of type 1 immunity in a mouse model of subcutaneous infection by Trypanosoma cruzi.

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João B Pesquero Research Topics

Disease

19	Inflammation (Inflammations) 01/2019 - 12/2002
7	Infections 06/2019 - 01/2003
6	Melanoma (Melanoma, Malignant) 03/2019 - 11/2003
6	Obesity 03/2017 - 02/2008
5	Hyperalgesia 01/2016 - 12/2002
5	Pain (Aches) 01/2016 - 12/2002
4	Neoplasms (Cancer) 02/2016 - 02/2002
4	Edema (Dropsy) 09/2009 - 01/2003
3	Neuralgia (Stump Neuralgia) 06/2013 - 03/2005
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 06/2013 - 11/2008
3	Ischemia 08/2008 - 01/2002
2	Malaria 06/2019 - 05/2012
2	Hypertension (High Blood Pressure) 03/2017 - 06/2008
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 12/2015 - 04/2005
2	Insulin Resistance 01/2015 - 01/2015
2	Weight Gain 01/2015 - 06/2008
2	Necrosis 04/2014 - 01/2002
2	Hypersensitivity (Allergy) 06/2013 - 06/2008
2	Shock 04/2013 - 07/2008
2	Body Weight (Weight, Body) 06/2008 - 02/2008
2	Post-Exercise Hypotension 02/2008 - 05/2007
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2020
1	Proteinuria 01/2020
1	Fabry Disease (Fabry's Disease) 01/2020
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2020
1	Inborn Genetic Diseases (Disease, Hereditary) 02/2019
1	Hereditary Angioedemas 02/2019
1	Tuberculosis (Tuberculoses) 01/2018
1	Atopic Dermatitis (Atopic Eczema) 08/2017
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 04/2017
1	Weight Loss (Weight Reduction) 03/2017
1	Gout 01/2016
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2016
1	Rickets (Rachitis) 01/2016
1	Osteomalacia 01/2016
1	Hypophosphatemia 01/2016
1	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 01/2016
1	Pathologic Processes 01/2016
1	Hyperphagia (Overeating) 01/2015
1	Overweight 01/2015

Drug/Important Bio-Agent (IBA)

35	KininsIBA 06/2019 - 01/2002
10	BradykininIBA 01/2019 - 12/2002
6	icatibantIBA 01/2018 - 05/2002
5	LeptinIBA 03/2017 - 02/2008
5	Messenger RNA (mRNA)IBA 08/2014 - 02/2002
4	Kininogens (Kininogen)IBA 01/2019 - 11/2006
4	LipopolysaccharidesIBA 04/2013 - 01/2003
4	2,5-dichloro-4-bromophenol (B 2)IBA 09/2009 - 12/2002
3	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 11/2007
3	Peptides (Polypeptides)IBA 01/2019 - 01/2011
3	EnzymesIBA 01/2016 - 02/2002
3	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2016 - 01/2003
3	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 01/2016 - 01/2003
3	Peptide Hydrolases (Proteases)FDA Link 01/2016 - 11/2006
3	LipidsIBA 01/2015 - 02/2008
3	CytokinesIBA 04/2014 - 02/2008
2	Captopril (Capoten)FDA LinkGeneric 06/2019 - 01/2003
2	Interleukin-10 (Interleukin 10)IBA 01/2019 - 02/2016
2	2- ((3- (1,3- benzodioxol- 5- yl)- 3- (((6- methoxy- 2- naphthyl)sulfonyl)amino)propanoyl)amino)- 3- (4- ((2,6- dimethylpiperidinyl)methyl)phenyl)- N- isopropyl- N- methylpropanamideIBA 01/2018 - 06/2008
2	Insulin (Novolin)FDA Link 04/2017 - 02/2008
2	des-Arg(9)- bradykininIBA 01/2016 - 12/2002
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 03/2007
2	CholesterolIBA 01/2015 - 10/2009
2	Glucose (Dextrose)FDA LinkGeneric 01/2015 - 01/2015
2	Enalapril FDA LinkGeneric 01/2015 - 02/2008
2	Cisplatin (Platino)FDA LinkGeneric 04/2014 - 07/2011
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2013 - 06/2008
2	tesmilifene (DPPE)IBA 07/2011 - 11/2003
2	Freund's AdjuvantIBA 01/2011 - 12/2002
2	Cysteine Proteases (Cysteine Protease)IBA 09/2009 - 01/2006
2	Bradykinin B1 ReceptorIBA 08/2008 - 04/2005
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020
1	GalactosidasesIBA 01/2020
1	NPHS2 proteinIBA 01/2020
1	Complement C1 Inhibitor Protein (C1 Esterase Inhibitor)IBA 02/2019
1	ElectrolytesIBA 01/2019
1	CarbohydratesIBA 01/2019
1	Interleukin-8 (Interleukin 8)IBA 01/2019
1	Interleukin-6 (Interleukin 6)IBA 01/2019
1	MicronutrientsIBA 01/2019
1	Isoleucine (L-Isoleucine)FDA Link 08/2017
1	Angiotensin IIIIBA 03/2017
1	Glutamyl Aminopeptidase (Aspartyl Aminopeptidase)IBA 03/2017
1	OsteopontinIBA 01/2016
1	Vitamin D FDA LinkGeneric 01/2016
1	Uric Acid (Urate)IBA 01/2016
1	Phosphates (Orthophosphate)IBA 01/2016
1	Metalloproteases (Metalloproteinases)IBA 01/2016
1	InterleukinsIBA 01/2016
1	EndopeptidasesIBA 01/2016
1	Lysine Carboxypeptidase (Carboxypeptidase N)IBA 01/2016
1	Streptozocin (Streptozotocin)FDA Link 12/2015
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2015
1	C-Reactive ProteinIBA 01/2015
1	Adenosine Triphosphate (ATP)IBA 01/2015
1	Triglycerides (Triacylglycerol)IBA 01/2015

Therapy/Procedure

4	Therapeutics 03/2019 - 02/2008
2	Drug Therapy (Chemotherapy) 01/2013 - 09/2011
1	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2020
1	Intra-Articular Injections 01/2016